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Unexplained rashes can be caused by allergies, abrasive clothing, and chronic fatigue syndrome. Allergies are a common cause, but the trigger is often unknown. Chronic fatigue syndrome can cause a rash, but it is rare and often undiagnosed. Autoimmune progesterone dermatitis is a rare condition that causes rashes in women due to hormonal changes during their menstrual cycle.
Some causes of an unexplained rash are an allergic reaction, abrasive clothing, and chronic fatigue syndrome. An allergic reaction is an especially common cause of unexplained skin rashes, but the patient often never discovers what they came into contact with that triggered the reaction. Chronic fatigue syndrome is a rarer cause, but researchers aren’t sure how rare it is due to poor understanding of the condition and the number of undiagnosed people worldwide. In some cases, the rash is caused by an immune response due to an autoimmune disease.
Often a mysterious rash is caused by an allergic reaction to a foreign or unusual substance. Sometimes allergic reactions are minor and only cause symptoms such as a rash and itching, but other times they can be more dangerous. One thing that often causes an unusual allergic reaction is a new laundry detergent, so it’s usually a good idea to consider new substances that have been introduced into an environment when trying to root out the cause of an allergic reaction. Stings from insects, foods, and other substances can also cause an allergic reaction and an unexplained rash.
Sometimes a rash is caused by something as simple as abrasive clothing or friction. New clothes are more suspicious than old clothes when people end up with an unexplained rash, possibly from abrasive material. Other times the rash is caused by friction, or friction against a person’s skin, clothing, or something else that irritates the skin and eventually causes it to break out in a rash.
Chronic fatigue syndrome is a condition in which the patient has unexplained tiredness for at least six months. There is no way to diagnose a patient with chronic fatigue other than ruling out all other potential causes of the fatigue and considering any other symptoms. Some people with chronic fatigue syndrome develop a mysterious rash, while others experience headaches and low-grade afternoon fever. As the causes of unexplained skin rashes range, this is thought to be quite rare, but the vast majority of people with chronic fatigue syndrome go undiagnosed.
Autoimmune progesterone dermatitis (APD) is a condition that causes women to develop rashes due to their menstrual cycle. This health problem is rare and not fully understood, but researchers believe the rash is a response to hormonal changes in a woman’s body. Women with APD develop a rash before their period, which goes away within a few days of their actual period. Those who undergo hormone therapy, such as taking contraceptive pills, may be more likely to suffer from APD.
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