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What’s a Hamilton Syringe?

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Hamilton syringes are not for human use but for laboratory procedures. They come in various types, including glass syringes for HPLC and GC, and implant syringes with a wheel assembly. Researchers use them for gel electrophoresis and to administer compounds to animals.

A Hamilton syringe is one of the syringes manufactured by the Hamilton company. These syringes are not intended for human uses such as injecting insulin or administering vaccines. Instead, they are intended to help researchers perform a number of common laboratory procedures. As a result, there are a wide variety of Hamilton syringes, designed specifically for a single purpose.

Many disposable syringes are made of plastic and are meant to be used only once. In the laboratory, certain procedures, such as high-performance liquid chromatography (HPLC) and gas chromatography (GC), are performed frequently, making a reusable syringe more convenient. For this reason Hamilton syringes intended for HPLC and GC are made of glass. Glass syringes can be autoclaved and cleaned after use. Additionally, the glass surface makes the syringes airtight, so volatile compounds can be delivered to an HPLC or GC device without escaping gas.

Certain types of Hamilton syringes are intended for use with certain sampling devices. These syringes can be manufactured to automatically withdraw and dispense specific volumes of liquid, without the user having to measure out the amount. Other manual syringes leave the amount of liquid to be sampled at the discretion of the user. These syringes may have removable needles, to ensure that no cross-contamination occurs between the sample source and the device.

In the life sciences, there is often a need for syringes to administer compounds to animals or to draw blood samples. Depending on the use and injection site, different varieties of Hamilton syringes may be appropriate. Disposable syringes with needles of different gauges are used for mice and rats, to account for differences in vein size in each species.

There is a need for a specialized Hamilton syringe for implantation of research embryos. Implant syringes typically have small volumes, to ensure a more accurate view of the volume. Unlike many syringes that use a plunger, implant syringes have a wheel assembly. The wheel allows precise withdrawal of small volumes of liquid and the wheel locks at a certain volume. The locking mechanism prevents the user from absorbing more liquid than is required for the procedure.

Researchers performing gel electrophoresis, a procedure that analyzes molecular weight, must load samples into several wells. For this purpose, a set of several syringes is used. The user can preset the volume of liquid to load and dispense and perform these actions simultaneously for all syringes. This assembly makes the gel loading process faster and more accurate.

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