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DMT is a potent psychedelic drug found in various plants and animals, and in small quantities in the human brain. It has been consumed throughout history by indigenous peoples, especially in South America, where it is consumed in shamanic rituals and called ayhuasca. DMT is a powerful hallucinogen, meant to be administered carefully in a quiet setting to someone who has previous experience with other psychedelic drugs. It is relatively rare due to a lack of commercial demand and a scarcity of people with the knowledge and motivation to isolate it from plants.
Dimethyltryptamine (DMT) is a potent psychedelic drug and a type of tryptamine alkaloid. It is a natural substance, found in various plants and animals, and in small quantities in the human brain, where its function is unknown. DMT is famous for its power. Although the psychedelic journey she creates lasts only 5 to 30 minutes when smoked, the high is deep and substantial, with the user feeling transported to a completely different place, immersed in kaleidoscopic sounds and sights. In its pure form, the drug is a white to yellow crystalline solid.
DMT has been consumed throughout history and prehistory by indigenous peoples, especially in South America, where it is consumed in shamanic rituals and called ayhuasca. This is done by combining the plant material that contains it with a monoamine oxide inhibitor, a special chemical that allows the drug to avoid digestion by the stomach and reach the bloodstream. Evidence of DMT consumption by indigenous peoples of South America dates back to at least 2130 BC. A pipe made from puma bone of that age tested positive for the substance. Smoking it would give users visions and sensations they associated with magical sources, putting them in touch with “spirits” they could consult on matters of plants, diseases, etc.
Some of the more unusual reports of psychedelic trips come from DMT users, reporting “spinning square vortices,” conversations with alien-type intelligent creatures, and so on. These reports are unusual in their intensity and the feeling of meeting intelligent beings, reminiscent of what happens to many people every night in dreams. Although scientific investigation into the drug’s effects has been limited, cognitive science may be able to learn more about the human brain by observing how its functioning changes in response to tryptamines. Spiritualists may be inclined to believe that beings that people “meet” under influence may actually exist in parallel planes, which has introduced alternative religious belief systems or experiential-based worldviews.
DMT is a powerful hallucinogen, meant to be administered carefully in a quiet setting to someone who has previous experience with other psychedelic drugs. The drug is relatively rare due to a lack of commercial demand and a scarcity of people with the knowledge and motivation to isolate it from plants. However, as a molecule, it seems ripe ground for discovery. Untested speculation has argued that DMT that occurs naturally in the brain may be implicated in certain neurological states and, when artificially administered, may flip these “switches and levers” in ways that can be more precisely characterized and studied. Since the human brain is the most complex known object in the universe, determining exactly how it interacts with complex molecules like this could be one of the greatest scientific challenges of all time.
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