Phosphatidylserine side effects are mild if taken in safe amounts, but can include thinning the blood when taken with certain drugs. It may improve mental function and benefit athletes, but safe doses for children and the elderly are not yet determined. Originally derived from cow brains, it is now sourced from plants, but may be less effective. When taken with anticoagulants like ginkgo, it can be harmful.
Phosphatidylserine side effects tend to be relatively mild as long as the user takes safe amounts of the medication. They usually only include mild gastrointestinal discomfort. When taken with other drugs, especially some types of blood thinners, phosphatidylserine side effects can include thinning the blood to unhealthy levels. Another concern when taking phosphatidylserine is that scientists have not fully determined the maximum safe doses of the drug for children or the elderly, so patients in these groups should take only small amounts of the drug.
Phosphatidylserine is a chemical that belongs to the phospholipid class of chemical compounds. It is an important part of the cell membrane, and the human body produces small amounts of it itself. There is some evidence to suggest that supplementing the body’s natural levels of phosphatidylserine may lead to better mental function. As a result, scientists believe the drug may help treat certain mental illnesses, including Alzheimer’s disease, depression, and attention deficit hyperactivity disorder (ADHD).
Initially, pharmaceutical companies used cow brains to obtain phosphatidylserine for supplements. However, there has been concern that this method could cause phosphatidylserine side effects including contracting harmful viruses, such as mad cow disease. Phosphatidylserine has been derived from plant substances, although there is evidence to suggest that the supplement is less effective when vegetables are its source.
There is also evidence to suggest that phosphatidylserine may be beneficial for athletes. The substance can cause a slight decrease in the release of cortisol in the body during a workout. Cortisol causes muscles to break down, which can limit muscle growth and lead to soreness, delaying future workouts. Limiting cortisol could help athletes build muscle faster. However, to achieve this benefit, an athlete must take large amounts of phosphatidylserine, which in turn subjects him or her to phosphatidylserine side effects to a greater extent.
The side effects of phosphatidylserine that are of most concern are those that involve its interaction with various anticoagulants. This problem arises more frequently when subjects take ginko. Ginkgo, like phosphatidylserine, helps with mental function, so it is not uncommon for subjects to take both drugs. However, ginkgo is a blood thinner, and evidence suggests that phosphatidylserine might increase ginkgo’s slimming effects, possibly to harmful levels. This could also be true when subjects take phosphatidylserine with other anticoagulants, such as warfarin, aspirin, pentoxifylline, clopidogrel, ticlopidine, garlic, and vitamin E.
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