Core needle biopsy: what is it?

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Core needle biopsy is a non-surgical procedure that removes a small sample of tissue for laboratory examination to detect cancer or other malignant diseases. It is a low-risk diagnostic technique that can be performed in a clinic or doctor’s office, and patients can return to their normal activities the same day. However, it is not recommended for areas of highly concentrated nerve tissue or other body regions of critical function.

A biopsy is a non-surgical medical procedure in which a small sample of tissue is removed for further laboratory examination under a microscope. It is most commonly performed to determine the presence of cancer or other malignant disease in the breast, skin, bone, marrow, and intestines. A core needle biopsy uses a long, thin, hollow needle with a special cutting edge to extract the tissue sample without disturbing or damaging the surrounding cellular structure. The needle is inserted through the skin into the affected area and a cylinder-shaped sample is removed. Several core needle biopsies may be required to obtain sufficient volume of affected tissue for laboratory examination.

After the patient receives a local anesthetic to numb the insertion site, the core needle is directed at the tissue to be extracted. Although some pressure may be felt during the procedure, patients should not feel any pain. The procedure may cause little discomfort to patients and they may experience pain, bruising, or minor bleeding from the point of needle insertion.

Core needle biopsies are a non-invasive, low-risk diagnostic technique that takes very little time to perform. They can be performed in a clinic or doctor’s office without subjecting patients to the stress and trauma of more traditional exploratory surgery. Tissue samples from core needle biopsies are examined under a microscope in a pathology laboratory, most commonly to determine the presence of cancer.

Although only small samples are taken from a core needle biopsy, it is not recommended for all biopsies of all parts of the body. A core needle biopsy should not be performed on areas of highly concentrated nerve tissue or other body regions of critical function. Areas such as the heart or lungs can be adversely affected or damaged by the procedure.

A core needle biopsy is not designed to remove the entire mass of tissue in question. As a result, there is a possibility that the removed samples may not contain the diseased or cancerous cells that would allow for a correct diagnosis. Despite this, the success rate for early detection of cancer from a core needle biopsy procedure is high which is why the procedure is so widely practiced.

A core needle biopsy does not require a hospital visit. Very little recovery time is required, meaning patients can have the procedure and return to their normal activities the same day in most cases. Developed specifically to reduce the risks and stress of previous surgical procedures, core needle biopsy has become a standard diagnostic method.




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