Age, health of sperm and eggs, number of embryos transferred, stimulation used, and laboratory procedures all influence the success of IVF. Women under 35 have the best chance of success, while men’s age can also affect fertility. The health of eggs and the number retrieved also play a role, as do the drugs used and laboratory procedures.
Many factors influence the success of in vitro (IV) fertilization. Among these are the age of the female involved, the age and health of the man providing the sperm, the health of the sperm, and the health and viability of the egg. The number of embryos that are transferred, the stimulation used and the laboratory procedures are among the factors that can also influence its success.
Age is one of the main factors influencing the success of IVF. As a woman gets older, her chances of successfully conceiving a child, even with the help of IVF, decrease. A woman’s best chance of IVF success is when she is under the age of 35. Women 35 and older usually have gradually declining success rates. Women who are over 40 typically have the lowest success rates.
Interestingly, the man’s age can also influence the success of IVF. While a man’s sperm may have the ability to fertilize an egg in the last few decades of a man’s life, some studies have produced evidence that male fertility may decline as a man ages. Therefore, a man in his 40s or older may be less fertile than a man in his 20s or 30s.
The health of a woman’s eggs and the number of eggs taken for fertilization can also influence the success of IVF. When a woman’s eggs are healthy, she has a better chance of achieving success through IVF. She also has a better chance of achieving success on the first try than a woman with less than optimal eggs. Likewise, the number of eggs retrieved for a procedure also affects its success. For example, success rates are better when six to 10 eggs are retrieved than when fewer than six eggs are retrieved; a person may have the lowest expectations of success when fewer than three eggs are retrieved.
Other factors that can affect IVF success rates are the drugs used to stimulate egg production and laboratory procedures. Hormones are commonly used to stimulate the development of more follicles that will release eggs during a cycle. The success of these hormones can greatly affect the number and health of the eggs that are retrieved. Laboratory factors, such as air quality, light and temperature can influence the success of IVF. The efficiency of those performing laboratory procedures can also affect success rates.
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