Elevated estradiol levels can indicate health problems, including fertility issues and cancer. Endometriosis, polycystic ovary syndrome, and hypopituitarism can also cause high levels. Hormone replacement therapy can restore levels, but close monitoring is recommended.
Estradiol is an important growth hormone in both men and women, and elevated estradiol levels can indicate the presence of a number of health problems. It’s important to note that elevated levels are completely normal during pregnancy and menstruation. In addition to these conditions, further medical tests are often needed if these hormone levels are higher than normal. High levels of estradiol can lead to fertility problems, especially in women, and increase the risks of developing cancer involving the reproductive organs. Males with high estradiol levels may be tested for certain types of cancer or may develop a condition known as gyno.
Endometriosis and polycystic ovary syndrome can cause some women to develop this condition. A medical condition in which cells that are normally confined to the uterus begin to grow in other areas of the body, endometriosis often causes severe pain, menstrual irregularities and infertility. Polycystic ovary syndrome can have many similar symptoms to endometriosis, although multiple cysts typically form on one or both ovaries in this condition. Tumors that may or may not be cancerous sometimes also develop in the ovaries, and elevated estradiol levels are commonly found in these cases. Women who have extremely high levels of this hormone may be at greater risk of miscarriage.
Some people who have high estradiol levels may also be diagnosed with a condition known as hypopituitarism. This is a relatively rare condition in which the pituitary gland does not properly produce one or more hormones needed to promote proper health. Growth, reproductive capacity, and blood pressure can be affected by this disorder, although the use of prescribed medications can usually control the symptoms of hypopituitarism. The patient may be referred to an endocrinologist, a doctor who specializes in treating hormonal imbalances and other conditions affecting the endocrine system.
Both males and females with high estradiol levels are at a higher risk of developing breast cancer or suffering a stroke. Symptoms that should be reported to a doctor immediately include swelling of the breasts, severe stomach cramps, or numbness affecting only one side of the body. In most cases, prescription drugs, often in the form of hormone replacement therapy, can restore hormone levels to a normal level, although close medical monitoring is recommended to properly assess estradiol levels over time. Any questions or concerns about elevated estradiol levels or the most appropriate treatment methods for an individual situation should be discussed with a doctor or other medical professional.
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