Cholinergic crisis: what is it?

Cholinergic crisis is caused by an accumulation of acetylcholine due to acetylcholinesterase inactivity or insufficiency. It can be caused by medication overdose, exposure to nerve agents, or post-surgical overdose. Diagnosis can be difficult, but a test using the drug edrophonium can help. Treatment involves the use of atropine. In cases of organophosphate poisoning, decontamination and […]

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