What’s “Call Shotgun” in a car?

“Shotgun calling” is a contest among passengers to ride in the front seat of a car, offering benefits such as control over the radio and climate. The practice likely originated from stagecoach days, but now serves as a convenience rather than a safety measure. The driver often has ultimate veto power. If you’d rather have […]

What is the Shotgun Method in genetics?

The shotgun method breaks up DNA into random fragments and sequences them using the chain termination method. Multiple reads are used to create a continuous sequence, but errors can occur due to repeating sequences. Next-generation sequencing is now faster but less accurate. The shotgun method is used to sequence long strands of a deoxyribonucleic acid […]

What’s a shotgun wedding?

A shotgun wedding is a hastily arranged marriage due to an unplanned pregnancy, often involving a gun-toting father-in-law. While the practice is not as common today, some families still believe in marriage before pregnancy to restore honor and gain respect from the community. The term can also be used metaphorically. In a Hollywood romance, life […]

What’s Shotgun Sequencing?

Shotgun sequencing breaks DNA into small fragments, clones, sequences and assembles them using computer analysis. Developed by Craig Venter, it competed with the Human Genome Project’s map-based sequencing. Whole genome sequencing bypasses mapping and starts with DNA sequencing, resulting in a contig. Shotgun sequencing is now the preferred method for genome sequencing. Shotgun sequencing is […]

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