How to manage sickle cell disease?

Sickle cell anemia causes hard, sticky, crescent-shaped red blood cells that block blood vessels, leading to painful crises. Management includes blood transfusions, supplements, and bone marrow transplants, but all have associated risks. Bone marrow transplants are the only cure but are not available to everyone. A genetic condition, in sickle cell anemia, the patient becomes […]

What’s a sickle bar?

A cutterbar supports cutting blades and can be easily changed for replacement or sharpening. It must be strong and flexible, made of steel, and rated for the intended application. Maintenance is important for safety, and technicians can be hired for special equipment. A cutterbar is a machine component that supports the blades used for cutting […]

What affects sickle cell disease frequency?

Sickle cell anemia is a genetic disorder affecting red blood cells, most commonly found in individuals with African, Saudi Arabian, or Mediterranean ancestry. Genetics and malaria prevalence are the main factors influencing its frequency, with different regions experiencing varying types of the disease due to spontaneous mutations. Sickle cell anemia is a genetic disorder characterized […]

What’s sickle cell anemia test?

Sickle cell tests can detect sickle cell disease or the gene, with newborns in the US routinely screened. Tests can be done on fetuses or adults, and confirmation may involve a hemoglobin S solubility test or evaluation for hemoglobinopathy. A sickle cell test is done to assess whether a person has sickle cell disease or […]

Causes of sickle cell anemia?

Sickle cell disease is caused by a genetic mutation in hemoglobin, specifically in chromosome 11, and is passed on through autosomal recessive inheritance. Individuals with sickle cell trait have a 50% chance of passing on the mutation to their children. Other contributing factors include low blood volume, dehydration, low blood oxygen levels, increased blood acidity, […]

Sickle cell anemia: what’s its history?

Sickle cell anemia was first identified in 1910 by Dr. James Herrick. It is a genetic condition that causes abnormal red blood cells, leading to low-oxygen blood and moderate to severe pain. Researchers have since discovered its relationship to oxygen, genetics, and hemoglobin, and continue to search for effective treatments and cures. While sickle cell […]

Sickle cell anemia & malaria: connection?

Sickle cell anemia and malaria are connected, with people who have sickle cell trait having greater resistance to malaria. However, some dispute the theory of natural selection linking the two diseases, and the fact that sickle cell disease sufferers often die prematurely raises further questions. Malaria has been spread to many tropical and subtropical regions […]

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