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Tryptophan supplements can be an effective treatment for depression in those who are serotonin deficient. Studies are ongoing to determine its effectiveness and any side effects. Tryptophan occurs naturally in foods, but must be taken in higher amounts for medicinal use. It should be taken with a vitamin B complex and on an empty stomach. More studies are needed to confirm the connection between tryptophan and depression.
Tryptophan and depression are linked because tryptophan supplements have been shown to be an effective treatment for depression in those who are serotonin deficient. Studies are still ongoing to determine how well this therapy works and if there are any side effects. Since tryptophan is a naturally occurring amino acid, it is believed that side effects should be minimal. The effectiveness of depression treatment will normally depend on the cause of your depression symptoms.
The link between tryptophan and the treatment of depression has been known for several years, although in some countries it was temporarily banned in supplement form after several individuals fell ill. This disease was actually caused by a contaminant in the supplements rather than the supplement itself, so the supplement is again widely available in most areas. There is a correct way to take it, however, and those who don’t do it correctly may not receive any health benefits.
Tryptophan occurs naturally in foods such as turkey or beef, but generally must be taken in much higher amounts for medicinal use. It is processed by the body to produce niacin, serotonin and melatonin. A deficiency in serotonin production is thought to cause depression in many individuals, so increasing its production may relieve symptoms. When tryptophan and depression treatments are used together, the effects can be intensified and it should not be combined with antidepressants until directed by a doctor.
Tryptophan should be taken along with a vitamin B complex so that it can be used to create serotonin rather than niacin. It should be taken on an empty stomach that is not in competition for absorption by the brain with other nutrients and amino acids. Sometimes it’s difficult for the brain to absorb the right amount of tryptophan, so doses may need to be adjusted to find an effective amount.
More studies are needed to confirm the connection between tryptophan and depression. Since it has not been used for this purpose for a long time, it is not known whether or not side effects or adverse reactions will occur in some patients. Patients are encouraged to ask their doctor or pharmacist before taking tryptophan, especially if it will be taken in combination with other medications or supplements.
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