Inflammation is the body’s response to injury, infection, or disease. A pro-inflammatory response can inhibit healing and perpetuate certain conditions. Treatment options include drugs, exercise, diet improvements, and other therapies.
Inflammation is the body’s natural protective response that can be activated when the homeostasis or balance of the body is disturbed or threatened. This automatic reaction also kickstarts the healing process to help the body get back to normal. Any type of injury, infection, disease, or damage to the internal or external body can trigger the inflammatory process. However, a pro-inflammatory reaction causes the body’s inflammatory process to be altered or exaggerated.
Common indicators of inflammation are swelling and pain with the affected area becoming red and hotter to the touch. These symptoms are directly related to the severity of the disruption of the body’s normal balance. When a pro-inflammatory response is elicited, side effects can be magnified. A pro-inflammatory response can also inhibit the progression of healing.
Pro-inflammatory cytokines are proteins that are normally made in cells and are a product of the immune system, the body’s process for keeping the body healthy and functioning at its peak. These proteins regulate the amount of inflammation produced by communicating with other cells throughout the body and regulating the immune system. However, in some cases, there is an overproduction of proinflammatory cytokines. This causes an abnormal response from the body and can inhibit healing or perpetuate certain conditions such as allergies, asthma, inflammatory bowel or pelvic disease, degenerative conditions such as rheumatoid arthritis, and systemic autoimmune diseases such as lupus.
Inflammation continues to be present as long as the body is injured or battling a disease or infection. A prolonged or unusual inflammatory reaction, such as seen when a pro-inflammatory response is present, can create a long-standing or chronic problem with symptoms associated with inflammation. This can perpetuate pain, swelling, warmth, and tissue color changes. In turn, this prolonged bout of irritation can result in the destruction of healthy cells surrounding the area or cells that are unrelated to the affected area. Continued pro-inflammation can also disrupt other bodily systems and cause a general failure in overall health.
Treatment for health-inhibiting pro-inflammatory responses includes a variety of drugs specialized to discourage cytokine production and help produce an anti-inflammatory reaction. These drugs are based on the health problem and the harmful results of the abnormal inflammation process. Other options include things like exercise and diet improvements or other therapies like melatonin treatments to help regulate the abnormal cytokine production.
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