What’s a Clinical Trial Database?

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Clinical trial databases list ongoing clinical trials by condition, drug, device, or stage. They are used by physicians, the public, and government regulators, and are maintained by government agencies, disease research organizations, and pharmaceutical developers. Clinical trials must be approved by ethics committees and registered with regulatory authorities. Clinical trial volunteers contribute to scientific research and can access the latest advances in treatment.

A clinical trial database is a list of ongoing clinical trials. People can search the database to identify evidence by condition, drug, device or stage. These databases can be used in many different ways by physicians, members of the public, and government regulators. Many are available online, provided free of charge by government agencies or organizations interested in scientific research. Organizations that sponsor clinical trials also maintain databases of ongoing trials and make this information publicly available.

In a clinical trial, medical researchers test a new drug, medical device, or treatment approach in a controlled environment. The goal is to determine if it is medically valid. Topics evaluated during a clinical trial include whether the test item works as expected, what the side effects and complications are, and how many people respond to it. The study goes through several phases. If the conclusion is that the study object is clinically useful, the clinical trial data is used to support an application to federal regulators to approve the drug, treatment, or device for sale.

Because clinical trials involve human subjects and their associated medical and ethical risks, they must be approved by ethics committees that review planned trial methodology. Additionally, when a clinical trial begins, it must be registered with government regulatory authorities that oversee medical research and the safety of medical treatments. These records are used to create a clinical trials database which describes all trials currently underway and provides information on the outcome of past clinical trials.

Government agencies aren’t the only groups maintaining databases. Organizations that research specific diseases usually maintain a database of clinical trials covering topics relevant to their interests. Similarly, pharmaceutical developers and medical device manufacturers maintain their own databases. At any one time, thousands of clinical trials of various sizes can be found in a clinical trial database.

Using a clinical trials database, members of the public can identify clinical trials they may be eligible to participate in. Clinical trial volunteers have access to the latest advances in treatment and care, contributing to scientific research that can improve safety and treatment options in the process. People can also track clinical trial progress if they’re interested in knowing when proposed treatments will be available to the public. Regulators follow a database of clinical trials to track trends that could indicate safety issues with the study, such as a high number of deaths in participants.




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