Metastasis is a malignant tumor that has migrated from a primary site to a secondary site. It can be difficult to diagnose the primary site, but examining the cells of the metastatic cancer can provide clues. Metastatic cancer cells develop their own blood networks to collect nourishment and can invade nearby blood vessels to migrate elsewhere. Medical researchers have recorded patterns in the behavior of these migrations to help locate the primary sites.
A metastasis is a migrated malignant tumor. A metastatic neoplasm, also known as a metastatic tumor, is a tumor whose cells have migrated from a primary site of cancer to a secondary site. As a diagnosis, metastatic neoplasm is a form of secondary cancer. A metastatic neoplasm is abnormal cell growths from an adjacent organ or cancer cells that have invaded organs at the second site after traveling through blood or lymph networks. Sometimes it takes a considerable battery of tests to discover the primary site of the cancer.
The primary site is the site in the human body where cancer first developed. The cells of a metastatic cancer can be carefully examined for clues about the composition of the first cells, sometimes leading to the discovery of the primary site. To ensure that both sites can receive treatment, the primary must be discovered. Another possibility is that a single cancer cell could travel through the lymph trunks or blood capillaries from an organ or tissue in a distant region of the body. For example, some forms of metastatic tumors in the brain arise from a primary tumor of the bladder.
A metastatic neoplasm, when it settles in a secondary site, develops its own blood networks to collect nourishment from adjacent tissues and capillaries. Cancer cells migrating through blood capillaries branch out to those blood capillaries or penetrate nearby blood vessel membranes to raid nourishment from the blood to grow. When the cancer invades nearby blood vessels, it can deposit its own metastatic cancer cells in the bloodstream to migrate elsewhere.
Metastatic cancer cells that survive the killer macrophages and white blood cells that constantly scan the bloodstream for diseased microorganisms often show a tendency to migrate from some organ areas to other specific organ areas. Medical researchers, pathologists, and oncologists have recorded patterns in the behavior of these migrations that can help locate the primary sites. Research on these topics is ongoing. Sometimes the presence of markers like these in metastatic cancers can indicate specific organs to receive imaging tests for the location of the primary sites.
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