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What’s a Micropipette?

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Micropipettes are laboratory equipment used to transfer and measure small amounts of liquid. They have an adjustment dial, plunger push button, and can measure volumes as small as 0.1 milliliters. Different sizes are available, with volume adjustment dials and digital volume indicators to ensure accuracy. The plungers stop at two positions, and disposable plastic tips are used to draw and release liquids. The volume adjustment dial regulates the volume of liquid entering the pipette tip.

Micropipettes are a common type of laboratory equipment designed to transfer and measure very small amounts of liquid. They can be used to measure volumes as small as 0.003 ounces (0.1 milliliters). Standard micropipettes used in lab settings come with a few basic parts including an adjustment dial and plunger push button. The plungers of the micropipettes are depressed with the thumb and, once released, the liquid can be drawn into a special plastic tip. Different sizes, types and styles of micropipettes are available.

The medium micropipette consists of several components including a volume adjustment dial and a digital volume indicator. At the end of a shaft, these pipettes also feature an attachment point designed to accommodate different types of disposable tips. Liquids are drawn into the disposable plastic tips fitted to the end of the micropipette shafts rather than the shafts themselves. The two primary buttons found on most micropipettes are the plunger button and the tip eject button. By pressing the eject button, the pipette will immediately release the disposable tip at the end of the device.

Most micropipette plungers are designed to stop in two different positions. By pressing the plunger into the first stop position and slowly releasing it, the pipette draws the desired volume of liquid into the disposable tip. Pushing the plunger of a micropipette further down to the second stop releases the volume of fluid drawn into the device at the first stop. To obtain an accurate measurement, the pipette plungers must be depressed to the first stop before the pipette tip is inserted into the sample.

Three of the most common micropipette sizes include P20, P200 and P1000. Each different size is designed to measure liquids in different volume ranges. The P20 micropipette can measure volumes between 0.02 and 0.7 ounces (0.5 and 20 milliliters) while the P200 can measure volumes between 0.7 and 6.8 ounces (20 and 200 milliliters). P1000 micropipettes are some of the largest micropipettes available and are typically used to measure liquids between 3.4 and 33.8 ounces (100 and 1,000 milliliters) in volume.

The volume adjustment dial on a micropipette helps ensure accurate measurement. This component is used to regulate the volume of liquid entering the pipette tip. As this dial is adjusted, the digital readout on the volume meter will change to reflect the adjustment.

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