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What’s a xenograft?

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Xenografts are tissues or cells from one species grafted onto another, commonly used to treat burn victims and in cancer research. They can also be used for organ transplantation when human organs are unavailable.

Xenografts are cells or sections of tissue that are removed from one species and grafted onto or into a different species. Grafts of this type are sometimes used to provide temporary protection from infection to burn victims, as well as in the cancer research process. In most cases, the xenograft is treated before the grafting takes place, which helps reduce the chances of the host body rejecting the harvested tissue.

A common use of xenograft is the treatment of humans who are missing significant sections of skin. Burn victims are one example. To facilitate the healing process, skin is taken from animals, processed to make the skin more compatible with the human body, then surgically connected or attached to the burn area. This helps minimize the risks of infection during the recovery period and allows the body to start rebuilding healthy skin cells on its own.

Along with burn victims, people suffering from other health problems may benefit from the use of xenotransplantation. Advanced-stage diabetics may receive a xenograft as a means of restoring a section of skin on the feet or legs that has deteriorated due to the disease. Cancer victims can receive this form of graft to repair damage to an internal organ.

There is a difference between a xenograft and the process known as a xenograft. A xenograft involves taking a complete organ for transplantation into a human host. This is likely to happen when there are no readily available human organs and the patient’s condition is critical. In some cases, the organs are harvested from pigs and successfully transplanted into humans. Although it is often used as a means of keeping the patient alive until a more suitable organ can be secured, some people are able to live for years with the use of animal organs, as long as the anti-rejection drug continues to help the body heal. accept the presence of the transplant.

It is not unusual for a xenograft to be used as part of cancer research. In this application, human tumors are removed from the host and grafted onto a laboratory animal, such as a rodent. The graft allows researchers to closely study the progress of the tumor as different experimental drugs and procedures are tried in an attempt to shrink the tumor and force the cancer into remission.

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