Arginine pyroglutamate, a dietary supplement, is believed to reverse aging effects by stimulating the pituitary gland to release human growth hormone. It also has vasodilation properties, improves immune system performance, and may help with sexual dysfunction and high cholesterol. However, high doses may enhance the growth of certain bacteria and viruses and increase cancer growth. Diabetic patients should avoid supplementation.
The amino acid arginine pyroglutamate, also known as growth hormone releaser, is believed by many to reverse the effects of aging. Unlike human growth hormone (HGH), arginine pyroglutamate is considered a dietary supplement by the Food and Drug Administration. The amino acid is taken orally and is becoming popular. Some studies suggest that high doses are required before beneficial results occur, while researchers believe that the various functions of this amino acid improve certain medical conditions and harm others.
In an effort to slow down the aging process, people are exploring ways to replace the substances responsible for providing a youthful appearance. These substances include arginine pyroglutamate and HGH, the production rates of which naturally decline with age. The amino acid easily crosses the blood brain barrier where it stimulates the pituitary gland to release HGH. Increased HGH levels combat the effects of aging, as the hormone promotes weight management by decreasing body fat and increasing muscle mass. The hormone must be given by injection because the digestive process would destroy it.
Arginine pyroglutamate supplements are taken orally, but should be taken on an empty stomach one hour before or three hours after a meal. Consuming the amino acid with other foods, antihistamines, and pain relievers decreases the protein’s ability to induce HGH production. The amino acid is naturally available in dairy products, meats, grains, nuts, and seeds, but healthcare providers suggest that 10 to 30 grams are required before reaching the desired level of HGH release.
Nitric oxide, which induces vasodilation and converts short-term memories into long-term memories, uses arginine pyroglutamante as one of its building blocks. As a vasodilator, the gas improves blood flow to various parts of the body, thus boosting the performance of the immune system. Researchers have discovered that high levels of nitric oxide are usually present in wounds. Health care providers have learned that increasing arginine pyroglutamate levels in a patient’s blood generally speeds the healing of fractures, accidental and surgical injuries.
The vasodilation properties associated with the amino acid have also reportedly helped people experiencing certain types of sexual dysfunction. Arginine pyroglutamate supplementation appears to improve vascular circulation in other ways, as it decreases cholesterol’s ability to stick to blood vessel walls, making the amino acid promising as a potential treatment for high cholesterol. When converted to nitric oxide, arginine pyroglutamate also breaks down ammonia, which typically accumulates in patients with impaired liver function.
The HGH-releasing properties of arginine pyroglutamate are not without their side effects, and studies indicate that HGH enhances the growth of certain bacteria and viruses, including pseudomonas and herpes. Increased growth hormone levels also increase cancer growth. Health care providers also generally advise against arginine pyroglutamate supplementation for diabetic patients, as the amino acid has insulin-blocking effects.
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