Calcium d-glucarate, found in vegetables and fruits, can detoxify the liver and potentially prevent cancer, lower cholesterol, increase metabolism, and remove excess estrogen. It is currently only taken for preventative measures and may interact with certain medications and alcohol.
Calcium d-glucarate is a chemical formed when calcium combines with glucaric acid, a naturally occurring substance found in vegetables such as broccoli and Brussels sprouts and some fruits such as oranges and apples. Studies have strongly suggested that calcium d-glucarate can detoxify the liver, potentially ridding the body of harmful carcinogens and hormones. The result may be a lower risk of cancer due to tumor prevention, as well as lower cholesterol levels and increased metabolism.
The body produces small amounts of glucaric acid, but these amounts are often not enough to have significant effects on the detoxification process. Doctors at the MD Anderson Cancer Research Center in Houston, Texas, discovered the potential health benefits of the chemical when they set out to find out why people with higher amounts of vegetables and fruits in their diets often had lower cancer risk. They gave the animals calcium d-glucarate and found that the supplement could help prevent tumor growth, even after the animals were given known carcinogens.
The supplement was sold and advertised to consumers as having several possible benefits for detoxifying the liver. Fewer toxins in the body can allow for greater immunity, helping to fight potential illnesses. Metabolism stimulation can be another positive effect of taking calcium d-glucarate. Low-density lipoprotein levels, also known as “bad” cholesterol, have decreased as a result of the supplement in laboratory tests.
This chemical also has the ability to remove excess estrogen from the body. This effect can help those who take steroids for health or performance-enhancing reasons, as steroids tend to flood the body with extra hormones. High estrogen levels are known to cause certain types of cancer, such as breast cancer. Studies are currently underway to determine if the ability of calcium d-glucarate to balance hormone levels is sufficient to prescribe the supplement to cancer patients.
Currently, no tests have been conclusive enough for approval of the supplement as a treatment; Calcium d-glucarate, for now, is only taken for preventative measures. No side effects have been found, but those who are pregnant or nursing should be cautious when taking any supplement. Due to the effects this chemical has on stimulating liver function, medications that the liver must break down may be adversely affected. Similarly, alcohol, which is processed in the liver, can inhibit the usefulness of the acid. Taking antioxidants along with the supplement can prevent the formation of cancer cells.
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