Dimethylisosorbide is a safe additive in cosmetics and drugs when used in diluted form, but can cause irritation at higher concentrations. It acts as a solvent and carrier, facilitating absorption into tissues. Safety controls ensure sufficient dilution, and consumers can consult safety databases for more information.
Dimethylisosorbide (DMI) is an additive in cosmetics and drugs that can increase absorption into tissues. When used in diluted form, it presents little risk to consumers. Higher concentrations can cause irritation, which can lead to inflammation, redness and a burning sensation. Pure dimethylisosorbide tends to be stable and safe to work with as long as chemists use reasonable precautions, such as face shields to limit facial exposure from flashbacks.
This compound is a clear, slightly oily liquid. It can act as a solvent and carrier to combine with ingredients and facilitate their absorption. When products with dimethylisosorbide are applied to the skin, it helps them penetrate instead of just settling on the surface. It can also be added to dental care products as compounds to strengthen teeth or reduce sensitivity, ensuring they have time to penetrate the tooth instead of being absorbed into the gums or accidentally ingested.
Absorption is necessary with skin care products to keep them from rubbing and messing around. In addition, it ensures deep and uniform coverage and guarantees a longer lasting treatment. Dimethylisosorbide can be added to moisturizers, sunscreens, and antiaging creams that are designed to penetrate the skin. Products with this additive shouldn’t leave a slippery or greasy feeling once they’ve finished saturating the skin, although it can take several minutes to fully absorb. During this time, it may be necessary to leave the skin exposed to avoid staining clothing.
Safety controls in manufacturing ensure that dimethylisosorbide is diluted sufficiently, usually in a 1 to 10% solution, to be safe. Products can be tested to confirm the level of dilution and ensure they are not causing irritation due to impurities or incorrect ingredient mixes. Consumers who notice irritation after applying products with dimethylisosorbide may be more sensitive to the compound or may have gotten a bad batch. In either case, the area can be washed with warm water and a mild soap to remove the chemical.
Consumers concerned about the safety of cosmetics with chemical ingredients that seem unfamiliar can consult a variety of resources for more information. Dimethylisosorbide, like other cosmetic additives, is listed in safety databases maintained by government agencies and non-profit organizations concerned with consumer protection. You can also review Material Safety Data Sheets, which provide guidance on handling chemicals. Consumers should be aware that these often refer to pure forms, rather than the diluted versions used in cosmetics.
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