What’s Estriol?

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Estriol is a natural estrogen produced during pregnancy in the fetus and placenta. Abnormal levels can indicate fetal problems. Estriol is weaker than other estrogens and is also present in men. Estriol levels can be high in women taking supplements. Abnormal levels on a quad screen may not be a cause for concern and further testing is needed to determine the situation.

Estriol is a natural estrogen associated with pregnancy. In pregnant women, estriol is produced in the fetus by the fetal liver and in the placenta. Estriol levels in blood and urine can be used to determine whether or not a woman is pregnant and to monitor the progress of the pregnancy. Abnormal levels of estriol can indicate that there is a problem with the developing fetus that could stand up to closer monitoring or further testing. Quad screen regularly recommended for pregnant women includes a check of estriol levels.

Two other natural estrogens are found in the body: estradiol and estrone. While many people think of estrogen as a female hormone, it is also present in men and plays an important role in fetal development whether a baby is a boy or a girl. Estrogens are produced from androgens, hormones associated with masculine traits, through the action of various enzymes in the body.

Estriol levels are typically highest in women of childbearing age and increase during pregnancy. Otherwise, estriol levels in women and men are quite similar, unless estriol is taken as a supplement. This hormone is sometimes used to manage menopausal symptoms and has also been used in the treatment of some other conditions. Estriol levels in women taking supplements can be very high.

This estrogen is much weaker than other natural estrogens found in the body. Also known as theelol, this hormone is a topic of interest among researchers who want to learn more about the role of hormones in the body and the role of hormones in various stages of life. It can be produced synthetically as well as being derived from animal sources for therapeutic use.

If a quad screen reveals abnormalities in estriol levels, this need not cause panic. Quad screens can be inaccurate and abnormal levels may be nothing to worry about. The only way to determine if glitches on a quad screen are a cause for concern is to undergo further testing to learn more about the situation. As with any type of health screen, it’s a good idea to talk to a doctor before testing to learn more about what the lab will be looking for, possible results, and the implications of those results. Being prepared in advance can make the experience less stressful.




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