What’s glandular cystitis?

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Glandular cystitis is a benign tissue change in the bladder lining that can be a symptom of another health issue or precede cancerous growths. It is commonly caused by chronic irritation and inflammation of the bladder and can be treated with medication or surgery. Patients with a history of this condition should be regularly screened for bladder cancer.

Glandular cystitis is a change that occurs in the tissue lining the bladder. This particular type of tissue change is benign, but it can be a symptom of another health issue that needs to be treated. Also, some cases of this condition precede the development of cancerous growths. For this reason, this finding may be cause for concern. A urologist usually diagnoses patients with this condition and provides them with information about treatment options.

Commonly, glandular cystitis is noticed during a bladder exam done for other reasons. The change can sometimes be seen on a procedure such as a cystoscopy, where a camera is inserted into the bladder. If a tissue biopsy sample is taken for the bladder, the condition will be visible under magnification in a laboratory setting. Staining can highlight cellular transformation and help a lab technician learn more about the extent of cellular changes.

This condition may be associated with Von Brunn’s nests, tissue clumps that form by budding of epithelial tissue within the bladder. Sometimes, these growths cause glandular cystitis, and in other cases, patients develop both conditions. The condition can be defined in terms of localization or spread and whether or not the involved tissue is mucinous. Diffuse mucinous glandular cystitis may be a cause for concern.

People most commonly develop glandular cystitis due to chronic irritation and inflammation of the bladder. People who wear a catheter can be prone to it, and this condition is especially common in quadriplegic and paraplegic patients. Similarly, people with a history of bladder infections, stones, and bladder surgery may be vulnerable to changes in bladder cell structure. When this condition is identified, it is important to determine the cause so that treatment can be provided.

Treatments for the cause may include medications and surgery. Once the patient has been treated, a follow-up exam can be used to look for further cellular changes. A patient with a history of this condition should ensure it is noted in their medical records so that other healthcare professionals are aware of the problem. It can become relevant when making decisions about the best way to diagnose and treat a urogenital health condition. Doctors may also recommend that such patients be screened for bladder cancer regularly because they are at increased risk of developing malignant tumors of the bladder.




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