Glycocyamine is a naturally occurring compound in the human body that is converted to creatine in the liver, aiding muscle building. It is recommended to take with creatine, betaine, and protein, and can benefit both creatine responders and non-responders. The optimal dose is 1,000-3,000mg per day, and it is suggested to combine with betaine to reduce negative effects. Common side effects include an increased risk of vascular disease and neurotoxicity. Consult a doctor before supplementing.
Glycocyamine is a compound that is naturally present in the human body. When it enters the liver, it is converted to creatine, which can be used to build muscle tissue. Glycocyamine is often also known as guanidinoacetic acid, or GAA, and can be found in various muscle-building products that contain creatine.
The compound is formed in the kidney from glycine and arginine. It is then transported to the liver, where it stimulates the production of creatine. Since glucocyamine can also be found in creatine products, it is often used by bodybuilders and strength training athletes to increase muscle mass and strength.
Some of the benefits of taking glycocyamine may include increased energy levels, increased muscle strength, and delayed muscle fatigue. It is also recommended to take this supplement along with creatine to maximize its muscle building effects. Other supplements that can be taken along with GAA include betaine, which is also known as trimethylglycine, and protein.
Some experts believe that individuals can be classified as creatine responders or creatine non-responders. Creatine responders will naturally react more favorably to creatine and have more noticeable effects when creatine is used. Non-responders are people who experience little to no noticeable results, even when properly supplemented with creatine. Glycocyamine is believed to favorably benefit both responders and non-responders, and this is another reason for its popularity.
It is recommended that people take between 1,000 and 3,000 mg (about one to three grams) of glycocyamine per day. This can largely depend on each individual’s fitness goal and muscle building requirements. Strength training athletes can increase their daily dose when necessary, and many bodybuilders take up to five grams of GAA per day.
Many researchers recommend combining GAA with betaine, as this supplement can greatly reduce the negative effects of GAA. The optimal dose of betaine is estimated to be approximately four times that of GAA. Additional benefits of betaine include reduced risk of liver and heart disease. Betaine can be found in shellfish, spinach, and various grains and can be taken in dietary supplements or in capsule form.
Common side effects that are associated with glycocyamine can include an increased risk of vascular disease and neurotoxicity. It is always recommended to consult a doctor before beginning any supplementation program and also determine the ideal dosage.
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