Kaempferol is a flavonol found in various foods that has protective effects on human health, including reducing the risk of heart disease and cancer. It is a strong antioxidant that prevents oxidative damage to cells and DNA and inhibits cancer cell formation and growth. It is also a phytoestrogen that can bind to estrogen receptors and block the binding of estrogen, potentially reducing breast cancer rates. Kaempferol supplements are available but should be taken with caution and under the guidance of a doctor.
Kaempferol is a polyphenol that is a type of flavonoid, known as a flavonol. It is found in various foods eaten by humans, including Brussels sprouts, tea, grapefruit, broccoli, apples, onions, red wine, and many berries. This compound has been found to have a protective effect on human health. Studies suggest that it protects against heart disease and cancer.
Several different flavonols appear to have protective effects on human health. This includes the compounds quercetin and myricetin. Kaempferol was specifically identified as a food ingredient that reduced the risk of fatal heart disease in women.
Also a strong antioxidant, this flavonol helps prevent oxidative damage to cells and DNA. It is believed to prevent arteriosclerosis by this mechanism. Protecting DNA from oxidative damage may also help protect against cancer by preventing mutations from occurring.
Laboratory studies have found that this natural compound inhibits cancer cell formation and growth. It has been found to be particularly effective in combination with quercetin. Kaempferol also seems to make cancer cells more sensitive to anticancer agents, including chemotherapy drugs.
Their consumption of broccoli and tea has been correlated with a decrease in ovarian cancer in postmenopausal women. This effect appeared to be specific to kaempferol and was not a general effect of flavonoid consumption. The amounts required for protection appeared to be two cups of broccoli per day, or four cups of green or black tea per day.
Kaempferol seems to have properties that work against estrogen, making it a phytoestrogen. This indicates that it can bind to estrogen receptors and block the binding of estrogen. Some types of breast cancer are facilitated by estrogen binding. Other phytoestrogens, such as genistein and daidzein, have also been implicated in reducing breast cancer rates. There have been studies linking kaempferol to decreased levels of breast cancer, but this flavonol has not received the prominence of other phytoestrogens.
Kaempferol supplements are commercially available. However, some people may be allergic to them. You should always consult with a doctor before taking any supplement. Natural compounds can have a variety of effects and can interfere with the metabolism of prescription drugs and other herbal preparations.
Kaempferol is also known as indigo yellow. It is responsible for the coloration of the bright yellow flowers of the tropical trees Acacia decurrens and A. longifolia. There is a commercial dye known as indigo yellow, but it has a different chemical structure than flavonol.
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