Pantethine is a biologically active form of vitamin B5 that can help reduce cholesterol levels and improve cardiovascular health. It is available in food and supplements, but daily intake is not recommended without consulting a doctor due to potential side effects and drug interactions. Pantethine has a mild laxative effect and can interact with medications, so caution is advised for those with kidney or liver disease, children, and pregnant or lactating women.
Pantethine is a dietary supplement that is a form of pantothenic acid, commonly known as vitamin B5, and is considered to be a more biologically active form of vitamin B5, meaning it has a more direct effect on the body. In the body, it is involved in the metabolism of food, the production of red blood cells, and also affects the adrenal system. Some scientific studies have shown that pantethine can help reduce elevated blood cholesterol and triglyceride levels and improve cardiovascular health. Its various properties have made it a popular supplement for treating high cholesterol and for other purposes, such as improving athletic performance. Daily intake of pantethine is not recommended, and a doctor should always be consulted before taking it as a supplement due to the risk of side effects and drug interactions.
Vitamin B5 is readily available in various foods such as avocados, peas, oats, and lentils, as well as in dietary supplements. In the body, vitamin B5 is converted to pantethine, which is then converted to a substance called coenzyme A that the body uses to metabolize fats, proteins, and carbohydrates into energy. It is important to note that the effects on cholesterol levels in several studies only apply to pantethine intake, not vitamin B5. Most of these clinical studies have used a daily dose of 600-1,200 mg. A lower daily dose of 300 mg has also shown some effects on cholesterol levels, but with more modest results.
It is not known exactly how this substance helps to lower cholesterol. One theory is that it increases the concentration of certain chemicals in the body that help lower cholesterol and triglyceride levels in the blood. Pantethine also appears to have beneficial effects on the cardiovascular system, possibly reducing the risk of stroke and heart attack. It is also used to treat the symptoms of allergies to formaldehyde, as well as a rare genetic disorder called cystinosis.
The side effects of pantethine are usually mild. Its laxative effect can cause diarrhea, and there is a risk of heartburn, nausea, and other gastrointestinal problems. It can also cause a higher chance of bleeding. More serious side effects are rare, but they can interact with various medications, including beta-blockers, blood thinners, and some diuretics, and it’s important to consult a doctor before taking this supplement. People with kidney or liver disease, children, and pregnant or lactating women should be especially cautious when taking pantethine.
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