Picamilon is a dietary supplement and nootropic medication made up of vitamin B3 and GABA. It is used in Russia as a prescription drug for depression and senile psychosis. It acts as a vasodilator and has an anti-anxiety effect, making it a nootropic compound. Its effects are evident in one hour and can last up to six hours. Negative side effects include headaches and nausea, and it should not be taken with other vasodilators.
Picamilon is a dietary supplement and a nootropic medication. It is a combination of vitamin B3, also known as niacin, and the neurotransmitter GABA. This supplement is taken orally, usually in powder or tablet form, and can cross the blood-brain barrier. Once in the brain, it is hydrolyzed into GABA and niacin.
This compound was originally created in 1961 by the All-Union Scientific Research Institute, located in the former Soviet Union. In Russia, this compound is sold as a prescription drug and is patented by a company operating in Moscow. It is used there as a treatment for depression and senile psychosis. In the United States, this compound has been approved for sale as a dietary supplement.
Picamilon’s function is twofold, as when the compound is broken down into its constituent parts in the brain, each has a different effect. Niacin acts as a vasodilator, which enlarges the blood vessels in the brain. This, in turn, leads to increased blood flow, reduced blood pressure, and is believed to help control migraine headaches.
When the second part of the picamilon compound, GABA, is activated in the brain, it is believed to create a mild anti-anxiety effect. This is known as an anxiolytic response, and it is because GABA is an inhibitory neurotransmitter. GABA limits, rather than encourages, certain brain functions.
Picamilon is considered a nootropic compound. They are also known as smart drugs, and are believed to stabilize mental function. For picamilon and many other nootropic drugs, there is little clinical research clearly showing their mechanism of action. Many people who take picamilon report feeling less anxious and more energetic, which is counterintuitive for anti-anxiety drugs. Most drugs that suppress anxiety reactions also cause feelings of depression or lethargy.
The typical dose of picamilon, for a healthy adult, is 100 milligrams (mg), one to three times per day. This compound works very quickly, since its effects are evident in one hour and can last up to six hours. It can have a mildly stimulating effect, so its use before bedtime should be avoided. The negative side effects of this supplement appear to be quite limited, but include headaches and nausea. One of the natural results of using the drug is significantly lowered blood pressure, so it should not be taken with any other vasodilator, especially those prescribed by a doctor.
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