Rimonabant is a diet pill that suppresses appetite by blocking the CB1 receptors in the brain, which are stimulated by cannabis and increase appetite. It is prescribed to clinically obese or overweight people at risk of heart disease and should be used in conjunction with a regulated diet and exercise. Side effects may include nervousness, anxiety, sleeplessness, and depression.
Rimonabant is a diet pill that has been shown to help people lose weight, especially those who are clinically obese or at risk for heart disease. It is licensed in some parts of Europe as Acomplia and in the United States as Zimulti. It has come to the diet pill market through a strange scientific twist of fate. When it came to the attention of scientists that smoking an illegal substance, cannabis, will not give the smoker “munchies,” or an increased appetite in simple terms, they began to wonder if they could reverse the process. If these receptors are stimulated during cannabis use, perhaps they can be blocked or manipulated to suppress appetite. Rimonabant is the drug that scientists developed to achieve this goal, and it has been shown to inhibit the areas of the brain that control the desire to eat.
The cannabinoids in cannabis stimulate the endocannabinoid system in the brain and cause an increase in appetite. Rimonabant works in the opposite direction and works to inhibit the hunger receptors in the brain and therefore suppresses the appetite. More specifically, it counteracts what are known as the CB1 receptors in the brain, which are known to affect lipid and glucose metabolism, obesity, and even smoking and drug habit. Additionally, Rimonabant promotes the production of the good cholesterols known as high-density lipoproteins (HDL) while lowering triglyceride levels.
People who are obese or significantly overweight are known to benefit from Rimonabant. The World Health Organization (WHO) says that an obese person has a body mass index of more than 25% fat for men and 30% for women (30 kg/m2). Rimonabant is only available by prescription and is only prescribed to those who are clinically obese and to overweight people who have a significant chance of heart disease. Of course, Rimonabant is not a panacea for weight loss and should be used in conjunction with a regulated diet and exercise. A doctor will need proof that a patient who asks to be prescribed Rimonabant first can lose some weight without the help of the drug.
Regarding side effects, Rimonabant is not believed to have significant or long-lasting effects. However, some patients have been known to experience feelings of nervousness or anxiety, periods of sleeplessness, and even depression. This is believed to be the result of the drug’s manipulation of the receptors in the brain. Based on most prescription medications, there is a chance that Rimonabant can also cause diarrhea and nausea.
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