What’s ubiquinol?

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Ubiquinol is a reduced form of CoQ10, which is essential for basic cellular function. Levels decline with age and serious illnesses. CoQ10 acts as a mediator of ATP synthesis and is a powerful antioxidant that can prevent age-related diseases. It also regenerates other antioxidants and is essential for producing blood lipids.

Ubiquinol is a reduced form of the coenzyme, Q10 (CoQ10). CoQ10 is produced within the human body and is required by all cells for basic function. Levels decline with a person’s age, and levels can be depleted when a person is suffering from serious illnesses such as Parkinson’s disease, heart disease, and cancer. CoQ10 can be acquired in small amounts from foods such as beef, broccoli, and fish, but is often supplemented if deficiency is suspected. CoQ10 was first identified in 1957 by scientists investigating the catalyst for metabolic functions within a cell. The scientists found that the substance is present in most cells of the body and that the highest concentration was present in tissues that have high energy requirements, such as the kidneys, heart and skeletal muscles.

The substance acts as a mediator of adenosine triphosphate (ATP). ATP synthesis is the mechanism by which cells generate energy to perform many cellular tasks, and a lack of ubiquinol leads to cell degeneration. Organs with high levels of ubiquinol were also found to be highly dependent on ATP production. CoQ10 owes its ability to act as an important metabolism booster to the ubiquinol cycle, a process that alternates between ubiquinone and another form of CoQ10, ubiquinone. This cycle, in addition to providing energy, is a process that protects cell membranes from oxidative damage.

CoQ10 is a powerful antioxidant, one of the few inherent antioxidants synthesized in the human body. As an antioxidant, it inhibits the oxidation process, which stops the formation of free radicals that can cause pathologies and rapid aging. There have been several studies on aging populations showing that declining levels of CoqQ10 are due to the decreased ability to convert ubiquinone to ubiquinol. Supplementation can encourage conversion and has shown promise in the treatment of age-related neurological diseases such as Parkinson’s.

Another way in which CoQ10 prevents age-related diseases is based on its ability to regenerate other antioxidant substances such as vitamin E or tocopheric and vitamin C, known as ascorbate. Free radicals can cause further damage to the body if these nutrients are depleted and not replenished. Ubiquinol is also an essential compound for producing blood lipids. Beneficial cholesterol, the lipid the body needs to keep arteries free of plaque buildup, is synthesized, in part, from ubiquinol and the other forms of CoQ10.




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