What’s Mutation Rate?

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The mutation rate is the probability of genetic mutations occurring within a single generation. High rates can help species adapt to changing environments, but many mutations are harmful to individuals. Low rates are good for individuals but make it difficult for species to adapt. Bacteria and viruses have high mutation rates, which can be problematic in disease-causing organisms. Mutation rates can also provide information about a species’ history.

The mutation rate is the rate at which organisms undergo genetic mutations, which can include simple genetic variations or more complex mutations that result in significant divergence from other organisms of the same species. The mutation rate is usually expressed as the chance of mutations within a single generation. People sometimes confuse mutation rates with mutation frequency: Rate refers to a probability of a mutation, while frequency actually involves counting the number of organisms with a particular genetic mutation.

A species that has a high mutation rate may find it easier to adapt to a changing environment. However, high mutation rates can be harmful to individuals because many mutations are not beneficial. Consequently, the high mutation rate would have caused the death of many individuals, while some would have developed to respond to environmental changes and perpetuate the species. This makes high rates good for species as a whole, but not for individual representatives.

A low mutation rate, on the other hand, is good for individuals, because their chances of being born with a mutation are relatively low. Low rates can be bad for species, however, because they make it difficult for organisms to adapt favorable mutations that help the organism respond to changes in the natural environment.

One of the classic examples of a high mutation rate is found in many bacteria and viruses. These organisms find it helpful to mutate rapidly, because they reproduce in large numbers, so losing numerous individuals does not harm the species as a whole. The high mutation rate also allows them to adapt to situations which may include needing to incubate for an extended period of time or the introduction of new drugs which kill off many individuals within the species.

High mutation rates can be a serious problem when they occur in disease-causing organisms, because it is difficult to eradicate these organisms from the body. HIV, for example, has an infamously high mutation rate that allows it to constantly evade new drugs introduced to combat it.

In addition to having an impact on the development of a species over time, mutation rates can also be used to glean information about a species’ history. The researchers tracked specific changes to determine when organisms genetically differentiated, using mutations that closely resemble clocks. By tracing mutations back in time, using data on an organism’s mutation rate, a researcher can estimate when two related species might have been the same species, or genetic research can find a common ancestor.




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